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ISSN 2063-5346
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SPECTRAL ANALYSIS OF SEED EXTRACT OF KALONJI (NIGELLA SATIVA) USING GAS CHROMATOGRAPHY-MASS SPECTROMETRY AND MEDICINAL POTENTIAL : AN OVERVIEW

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Manisha and Dr. Mahesh C. Sharma
» doi: 10.31838/ecb/2023.12.s1.125

Abstract

Nigella sativa linn commonly known as kalonji or black seed, member of Ranunculaceae family, widely used in various traditional medicinal systems like Ayurveda and Siddha. Its Seed and seed oil has been considered as diuretic, carminative, vermifuge and lactogogue. Extensive pharmacological studies reveals the antimicrobial, anti-inflammatory, antidiabetic, immune potentiating, antitumor, antimicrobial, CNS depressant and antihistaminic activities of seeds extracts. Maximum therapeutic properties of black cumin are due to the presence of essential oil major component thymoquinone. The present study evaluate the phytoconstituents present in the pet ether, chloroform and acetone seed extracts. A total of 28, 13 and 17 components are identified from the gas chromatography and mass spectroscopy (GC-MS) analysis of pet ether, chloroform and acetone extracts of seeds respectively. The structure and formula of phytoconstituents present in different solvents predicted by the GC-MS reports.

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