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ISSN 2063-5346
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REVIEW ON PHYTOSOMES: A NOVEL DRUG DELIVERY SYSTEM

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Satyanarayan Sen, Reenu Yadav, Jyotiram Sawale, Gaurav Jain, Sonam Kushwaha, Monam Kushwaha, Shipra, Jitendra Malviya
» doi: 10.31838/ecb/2023.12.s2.227

Abstract

As dietary supplements for the homeostatic management of inflammation, toxins, malignancies, weight reduction, and other chronic or acute degenerative illnesses, plant-derived products or plant extracts are gaining more and more attention. However, issues with stability and bioavailability are common with these medications. After being isolated, plant compounds become unstable and may therefore be unable to penetrate the bio membrane. The phytosome method significantly decreases these tasks. The phytosome or herbosome approach improves the lipophilicity of hydrophilic phytoconstituents sufficiently to pass biological membranes and increases the hydrophilicity of highly lipophilic drugs, making them appropriate for drug delivery. It is asserted that phytosome promotes the oral and topically applied absorption of "conventional herbal extracts" or isolated active ingredients. Due to the high demand for and use of plants or medications based on herbs, phytosomes are becoming more and more popular as prospective drug delivery systems. This study emphasises phospholipid chemistry, production, characterization, structural verification, benefits, contemporary research, & their use to increase the bioavailability of active herbal phytoconstituents. It also discusses the special feature of phospholipids in medication delivery. Prospectuses for novel drug regimens can suggest fresh avenues and boundless frontiers using phytosome technology.

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