A simple, Accurate, precise method was developed for the estimation of the Molnupiravir in bulk and pharmaceutical dosage form. Chromatogram was run through HSS 100 x 2.1 mm, 1.8m. Mobile phase containing 0.1N OPA: Acetonitrile taken in the ratio 55.89 (%v/v) and 44.11 was pumped through column at a flow rate of 0.2 ml/min. Temperature was maintained at 30.66°C. Optimized wavelength selected was ACQUITY TUV ChA 260.0 nm. Retention time of Molnupiravir was found to be 1.413 min. %RSD of the Molnupiravir was found to be 0.4 %Recovery was obtained as 100.02% for Molnupiravir. LOD, LOQ values obtained from regression equations of Molnupiravir were 0.08, 0.23. Regression equation of Molnupiravir is y = 42046x + 4850.1. Retention times were decreased and that run time was decreased, so the method developed was simple and economical that can be adopted in regular Quality control test in Industries.