Restoration of craniofacial defects with autogenous reconstruction are limited. Hence a prosthesis may be preferred for rehabilitation of the defect. Previously skin adhesives, eyeglasses, and anatomic undercuts in the defect area were commonly used as aids for the retention of the prosthesis, yet the results were not satisfactory both for the clinician and the patient. However, skin adhesives caused adverse skin reactions, deformation at the edges of the prosthesis, loss of adhesion due to perspiration, and extensive tissue coverage to increase retention while eyeglasses and undercuts provide insufficient retention accompanied with discomfort to the patient. Prostheses retained by extra oral implant retained increased life span of the prosthesis with improved retention and stability. These extra oral implants are safe, reliable and most effective method of retaining maxillofacial prosthesis with high survival rate thus providing enhanced comfort for the patient and ease of maintenance. However careful patient selection, pre-surgical evaluation of both systemic status and bone quality at the implant site, along with the patient’s interest to perform daily home care, must be done to achieve a successful result on long term basis.