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ISSN 2063-5346
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Potential Anti-Diabetic Herbs and Polyherbal Formulations: A Review

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Dr.A.R.Shinde, Dr.S A Surale-Patil, Dr.P.S Salve
» doi: 10.48047/ecb/2023.12.s2.324

Abstract

High blood glucose levels are a defining feature of the chronic metabolic illness known as diabetes mellitus, which is also linked to a number of problems. The use of herbal treatments and polyherbal formulations as potential complementary or alternative medicines for the management of diabetes has drawn a lot of attention. The purpose of this review study is to investigate the potential anti-diabetic properties of herbal remedies and polyherbal blends. Herbs with immediate effects on glucose metabolism are the main topic of the first part. Cinnamon, fenugreek, and bitter melon have all demonstrated encouraging outcomes in lowering blood sugar levels and enhancing insulin sensitivity. In addition, the anti-inflammatory and antioxidant properties of amla, ginger, ginseng, and turmeric can aid in the management of diabetes and its complications. Herbs that alter insulin signaling pathways are covered in the second section. The potential to increase insulin secretion, improve insulin sensitivity, and lower postprandial hyperglycemia has been shown for Gymnema sylvestre, bilberry, ginkgo biloba, and Salacia species. The importance of polyherbal formulations in the treatment of diabetes is highlighted in the third section. Through the combination of several herbs, Triphala, Diabecon, and Nishamalaki have demonstrated synergistic benefits that target various parts of the pathophysiology of diabetes. The potential of herbal treatments and polyherbal formulations is supported by the evidence, but further study is required to establish the best dosages, standardized methods, long-term safety, and any potential herb-drug interactions. To ensure the incorporation of herbal treatments into standard diabetes therapy, cooperation between traditional medicine practitioners, researchers, and healthcare professionals is crucial. In conclusion, herbal treatments and mixtures of herbs present potential ways to manage diabetes. The creation of herbal medicines that are supported by scientific evidence and complement current treatment modalities can benefit from the integration of traditional knowledge with rigorous scientific study.

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