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ISSN 2063-5346
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OPTIMIZATION OF QUERCETIN LOADED FAST DISSOLVING FILMS BY EMPLOYING QBD AS A DESIGNING TOOL FOR IMPROVED BIOAVAILABILITY

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Pidugu Shivaji Ashok Chakravarthy1, Srikar Grandhi2, Rajan Swami1, Inderbir Singh1*
» doi: 10.31838/ecb/2023.12.si5.010

Abstract

Quercetin was found to be BCS class-4 molecule with desired cancer preventive activity but characterized by lower solubility and permeability. To overcome the issues associated with Quercetin, the current research was designed for the development of cyclodextrin based inclusion complexes loaded orally fast dissolving films (ICQF). For the preparation of ICQFs, the film former, plasticizer and the super disintegrant was selected as methyl cellulose, PEG 400, either croscarmellose sodium/ starch citrate respectively

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