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ISSN 2063-5346
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MODERNIZED SYNTHESIS OF ACECLOFENAC WITH METHOD ANALYSIS & VALIDATION

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Anjali Kannojiya1* , Jyoti Maithani Kalra2 , Kapil Kalra3 , Rajeev Kumar Sharma4 , Saurabh Singh5 , Monika Gariya6 , Shagil Saltan7
» doi: 10.31838/ecb/2023.12.si5.0139

Abstract

Aceclofenac chemically called as 2-[(2,6-dichlorophenyl) amino] phenylacectoxyacetic acid. The aim of the article is to represent the modernized method for the preparation of aceclofenac as the ancient method consume extremely long time to synthesize aceclofenac so modernized method is developed for the synthesis of aceclofenac which is time saving and high yielding. UV spectrophotometric techniques are employed for the method analysis and validation. Titration method, ordinary method, and modified method were all devised for the analysis of Aceclofenac; the modified method for analysis uses method A (zero order), B (first order), and C (Area under curve). The absorption maxima were determined to be 274.65nm for method A (zero order), 259nm for method B (first order derivative), and measured between 269 and 279nm for method C (area under curve)

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