HIV or “Human Immunodeficiency Virus” significantly affects the immune system of the body and this decreases the ability of the body to fight against infectious viruses and bacteria. In this regard, effective HIV treatment should be implemented in health sectors in order to educate ordinary people and reduce the risks of transmission of the virus. It is identified that ART therapy is crucial to minimise the transmission of HIV and this treatment is provided in every public hospital and HIV treatment clinic. This treatment is significant as it lowers the viral load from the body therefore strongest the immune system of the body that gives the ability to resist the entrance of pathogens into the body. It is identified that in the treatment of HIV, the knowledge, skills and experience of the nurses are critically important as it affects the treatment of the HIV infected peoples. In this regard, a piece of good knowledge about HIV and AIDS is critically important to the nurses in order to reduce stress, anxiety, depression and fear from the mind of the patients. In order to conduct the study, a secondary data collection method is used. In this study, the secondary data is analysed with the help of thematic analysis, evaluating the relevant journals and articles from authentic sources in order to maintain the originality and authenticity of the study