Background: Globally, the prevalence of childhood obesity has risen in recent years. The International Association for the Study of Obesity (IASO) and International Obesity Task Force (IOTF) estimate that 200 million school children are either overweight or obese.1 Objective: To examine systematically the evidence from randomized controlled or clinical trials (RCTs) and Quasi experimental research design to identify how family/parents have been involved in childhood obesity home based intervention and to examine the effects of multidisciplinary lifestyle intervention to treat overweight/obese children and adolescents. Search strategy and Data Sources: Studies were electronically searched using Pubmed, Medline, Embase and Cochrane database from 2003 to 2021. Studies based on the selected inclusion criteria as well as the intervention for Obesity and the research Design. Results: One hundred and seventy two articles were identified through the five databases and cross referencing. At the end 9 articles were selected based on criteria. Conclusion: A family-based multidisciplinary approach is effective in the the health status, nutritional habits and physical performance in children