Gastric retention drug delivery systems are widely used to prolong the residence time of dosage forms in the stomach. Floating-in situ formulations, among other approaches, provide longer drug release and gastric residence time with the advantages of oral liquids. This study sought to construct and evaluate floating in situ gels of fluvastatin using various polymers such as xyloglucan, locust bean gum, Gaur gum, Karaya gum which undergo a pH-dependent sol-gel transition at gastric pH, thereby extending shelf life. chewing gum. System in the stomach. Sodium alginate is a natural polymer used as a gelling agent in which gelling is initiated by the presence of calcium ions in the form of calcium carbonate. Studies on the relationship between drug and polymer using FTIR studies have shown that there is no interaction between drug and polymer. In vitro parameters such as gel properties, total swimming time, drug content, viscosity and in vitro dissolution were examined for analysis. Among all formulations, the F12 formulation containing bison gum was chosen as the optimized formulation showing the highest drug release at the end of 12 hours with good buoyancy properties and gastric retention. From kinetic studies, the formulation showed a zero-order release with a superstate II transport mechanism.