Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Volume - 13 | Issue-1
Aim: To evaluate the salivary HNP1-3profile in children with and without Early Childhood Caries. Materials and Methods:A pilot study with a convenience sample (n=10) were included in the study and were divided into two groups. Group 1 – children with early childhood caries (n=5) and Group 2 – children without early childhood caries (n=5). Saliva samples were collected and salivary HNP1-3 levels were analysedusing Liquid chromatography mass spectrometry. Results:Pool chromatograms showed qualitative differences in HNP1-3 (1744 m/z) profile, noted in peaks 14 and 21, were present in the caries free pool, but absent in the ECC pool. Conclusion:A decrease in the salivary peptides HNP1-3 profile in children with ECCcan help establish specific preventive and treatment protocols.