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ISSN 2063-5346
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EVALUATION OF VASCULAR HEALTH BY CAROTID INTIMA-MEDIA THICKNESS IN EGYPTIAN PRE-DIABETIC PATIENTS

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Shrook Mousa, Mohamed Mahmoud, Sahar Alwakil, Alaa Abdelhamid1,2, Aasem Saif, Samar Aboulsoud
» doi: 10.48047/ecb/2023.12.si4.349

Abstract

Endothelial dysfunction (ED) is one of the major pathophysiological links between exposure to cardiovascular risk factors and the early development of atherosclerotic disease. It represents an initial reversible step in the development of atherogenesis. The identification of early stages of atherosclerotic diseases in diabetic and pre-diabetic persons is a fundamental step in the risk stratification protocols adopted by physicians in order to have a complete overview of the clinical status of such individuals. Carotid intima-media thickness is instrumental tool for the detection of early impairment in cardiovascular system and to stratify the cardiovascular risk of individuals. The aim of our work is to estimate the arterial wall thickness by carotid intima-media thickness CIMT. In our study CIMT is statistically higher in the pre- diabetic group (0.63±0.08 mm) than the control group (0.59±0.09 mm; p value 0.006). The current study shows that arterial thickness start early in patients suffering pre-diabetes and emphasizes the importance of early detection and treatment to prevent cardiovascular affection in such individuals.

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