COVID-19 is a disease caused by SARS-CoV-2 infection. Due to the increased spread of COVID-19 in various countries, WHO declared the covid 19 disorder a pandemic. Examination of IgM and IgG antibodies with immunochromatographic principles is considered easier to do than other tests and can be used as an initial suspicion of SARS-CoV-2 infection. This study aims to detect anti-SARS-CoV-2 IgM and IgG antibodies in Gorontalo City adolescents aged 17-25 years. The type of research used is descriptive research with a cross-sectional research design. The sample was an employee of the Sulawesi River Area Center. As many as 112 0rang were obtained through a simple random sampling technique. Antibody detection was carried out by dripping rich serum on the examination device and interpreted based on the theory and results of previous research. The results showed that 32% gave reactive IgM and IgG results, and 24% gave reactive IgG results. And there are 106 employees, 44%, who provide non-reactive IgM and IgG results. Conclusion During the transition period of the Covid-19 pandemic, IgM and IgG were still detected in adolescents aged 17-25 years in Gorontalo City.