The aim of this study was to explore the factors associated with the occurrence, subsequent prognosis and need for additional medications following cutaneous adverse drug reactions (ADRs) among inpatients and their Pharmaco economic status. To evaluate the clinical patterns of various drug induced cutaneous reactions and their economic impact on patients admitted in hospital. To evaluate the clinical patterns of various drug induced cutaneous reactions. An Ambispective observational study was conducted in a tertiary care Teaching hospital of dermatology department. The data of in-patients of 1 unit of the department of dermatology and therefore the in-patients referred from other departments thanks to cADRs were included within the study. The diagnosis of the cADR was made by the dermatologist supported on clinical and morphological grounds. The cost incurred in managing the documented cADRs was calculated supported the full total amount spent on the patients with cADR divided by total number of patients with ADRs. The outcome of this study may useful to predict and prevention of ADRs early, therefore reduces the treatment cost of Internal medicine wards which ends up with in the effective healthcare budget of the hospital.