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ISSN 2063-5346
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COMPARATIVE GC-MS ANALYSIS OF PHYLLANTHUS EMBLICA AND TERMINALIA BELLIRICA FRUITS EXTRACT TO IDENTIFY ACTIVE CHEMICAL PHYTO CONSTITUENTS

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Himani Badoni1*, Nishesh Sharma2 , Neha Arya3 , Ayushi Chaudhary4 , Pooja Saklani5 , Promila Sharma 6 , Meenakshi Pant7 , Rohit Bisht
» doi: 10.48047/ecb/2023.12.si5a.033

Abstract

Background: Phyllanthus emblica L. is a native of the family Phyllanthaceae, generally famous by Indian gooseberry or amla. It is used as a traditional medicine for the treatment of different diseases. Terminalia bellirica (Gaertn.) Roxb is commonly known as Baheda and widely beneficial in the traditional Indian medicinal system for centuries as a remedial source in various diseases. Methods: In the present study, Phytochemical analysis of aqueous methanol fraction of Phyllanthus emblica L. (PEAM) and Terminalia bellirica (Gaertn.) Roxb (TBAM) fruits was done. Antibacterial activity was tested against S. aureus (MTCC 6908), E. coli (MTCC 1698), P. aeruginosa (MTCC 4306) and K. pneumoniae (MTCC 9544). To analyse chemical composition of PEAM and TBAM, GC-MS analysis has been performed. Results: Overall 27 chemical components in PEAM and 38 components in fruits of TBAM were identified. The major components identified in the PEAM fruit extracts were 5-Hydroxymethylfurfural (30.61%), 1,2,3- Benzenetriol (24.78%), 9,12-Octadecadienoic acid (Z,Z) (9.52%) whereas other constituents were present in relatively small amounts. In TBAM fruit extracts the chief chemical components were 1,2,3-Benzenetriol (52.59), Oxacycloheptadec-8-en-2-one (20.66%), 5-Hydroxymethylfurfural (7.85%), respectively. Conclusion: The phytochemical analysis of PEAM and TBAM showed presence of diverse range of phytochemicals and antibacterial assessment of these extracts showed efficacy against different pathogenic bacterial strains. The results of GC-MS analysis illustrated the existence of numerous chemical constituents in fruits of PEAM and TBAM and are recommended as potential drug candidates of pharmaceutical significance.

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