Gac fruit (Momordica cochinchinensis), watermelon (Citrullus lanatus), and tomato fruit (Solanum lycopersicum) are high in natural antioxidants and have anticancer properties. Gac is a rich source of lycopene. These are commonly used in cancer, hypertension, dyslipidemia, inflammation, wound healing, anti-wrinkle products, moisturizers, and ulceration. In the present study, the freeze-dried powder of juices from the fruits of Momordica cochinchinensis (MC), Citrullus lanatus (CL), and Solanum lycopersicum (SL), as well as - carotene (BC), are evaluated, using ascorbic acid (AA) as a reference standard. Three herbal products wise Sample-A MC, Sample-B CL, Sample-C SL, and -carotene as sample-D were evaluated for invitro antioxidant activity. Free radical scavenging properties assessed by five invitro methods are DPPH, hydrogen peroxide (H2O2), superoxide, ferrous reducing antioxidant capacity assay (FRAC), and nitric oxide radical-scavenging activity. All the products were found to have potent antioxidant activity, which was significant (P <0.05) compared to ascorbic acid. All the assays were performed in triplicate, and the results are represented as mean SD. P values are calculated by ANOVA at a 95% confidence interval by GraphPad Prism 8.0.2.