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ISSN 2063-5346
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ANTIBIOTIC USAGE IN PATIENTS HAVING UNDERGONE CAESAREAN SECTION

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Shamshath Begum. M, Gunjan, Kashmira J Gohil, Sriram. A
» doi: 10.31838/ecb/2023.12.s2.246

Abstract

Caesarean section (CSEC) is one of the most common types of surgery done in both rich and poor countries. A prospective study of 75 prescriptions of women attending the inpatient and outpatient Department of Obstetrics and Gynaecology, a Tertiary Care Hospital, Agra. Among the 75 patients 40 developed mild to moderate surgical site infections giving a cumulative incidence of 44%. The age of study subjects ranged between 20 to 40 years. Majority (60%) of them belonged to 20-30 years group. The median preoperative length of stay (LOS) was 3 days. Cephalosporins cefuroxime 52%, cefuroxime 20%, Cefotaxime 12% were used pre operatively. Other antibiotics (e.g. Metronidazole, vancomycin, followed by amoxicillin+ potassium clavulanate) were used to treat post-surgical infections. The recommended regimen of ceftriaxone alone does not work against frequent isolates. Metronidazole was preferred as second line agent and used as extended spectrum regimen. This study found that there were a lot of SSIs after CSEC and that most of the pathogens that caused them were resistant to the antibiotic strains. Most SSIs caused by CSEC are found after the patient has left the hospital. A caesarean section that is done too quickly or without enough antibiotics is a major risk factor for SSI. This information is important for making targeted plans for surveillance and reducing the number of infections that happen after surgery. More research needs to be done to find out which set of interventions is best for preventing SSI after CSEC and improving patient outcomes.

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