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ISSN 2063-5346
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A STUDY TO DETERMINE THE MEAN PLATELET VOLUME (MPV) IN SUBJECT WITH DM.

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Priyank Shah1 , Shrikant Choudhary2 , Sumeet Garg3 , Vinit Kumar4*, Ram Kishan Jat5 , G.N. Saxena6 , Puneet Rijhwani7 , Mohammed Shoaib8 , Krutarth Shah9 , Manish Pahadia10, Pradeep Agarwal11, Bhavesh Gauswami
» doi: 10.31838/ecb/2023.12.si5.082

Abstract

Introduction- diabetes mellitus is a global pandemic. The increased platelet activity may play a role in the development of vascular complications of this metabolic disorder. The mean platelet volume (MPV) is an indicator of the average size and activity of platelets. Larger platelets are younger and exhibit more activity. Aim- To determine MPV in subject with Diabetes Mellitus. Material and Methods: Platelet count and MPV were measured in 100 T2DM patients and 100 Non Diabetic patients. Result: The mean platelet count and MPV were higher in diabetics as compared to non diabetic subjects. [277.5 +_ 81.3 vs 269.8+_ 70.8 ] (P = 0.256), 10.3 +_ 0.7 vs 7.4 +_ 0.8 (P = <0.000) Conclusions: Our results showed significantly higher MPV in diabetic patients than in the nondiabetic subjects. This indicates that elevated MPV could be either the cause for or due to the effect of the vascular complications. Hence, platelets may play a role and MPV can be used as a simple parameter to assess the vascular events in diabetes.

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