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ISSN 2063-5346
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A PROSPECTIVE COMPARATIVE STUDY ON EFFICACY OF CINNARIZINE AND BETAHISTINE IN PATIENTS WITH PERIPHERAL VERTIGO

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Swathi Suresh1* , Rukaiah Fatma Begum1* , MariyaElsJohny2 , Nirenjen S1 , Bhuvaneshwari S 3 , Kirubakaran N3 , Koushik Yetukuri4
» doi: 10.48047/ecb/2023.12.si5.0141

Abstract

Background: Peripheral vertigo is described as dizziness most often associated with loss of hearing, ringing in ears and difficulty focusing vision. Dizziness affects 15%-20% of adults yearly in large population-based studies where one in four cases represents vertigo. 12-month prevalence being 5% and annual incidence being 1.4%, vertigo remains an issue to be addressed. Methods A therapeutic decision which corresponds to optimal therapy in this regard is of prime importance. We compared the efficacy of two commonly prescribed drugs in peripheral vertigo to ease the therapy for vertigo. The primary objective of this study was to assess the relative efficacy of Cinnarizine and Betahistine in patients with peripheral vertigo. Results: The mean Unterberger- Fukuda Test (UFT) score for anteroposterior displacement between the two groups at 2 weeks showed significant difference (52.38 vs 66.6; P=0.01). Similarly, UFT score for angular deviation also showed positive results supporting Betahistine therapy (31.4 vs 38.57; P=0.03). Conclusion: Group I who received Betahistine showed better results when compared to group II who received Cinnarizine. The results indicate that Betahistine can be considered as predominant and more effective medication than Cinnarizine for peripheral vertigo.

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