Background: Hypertension ranks seventh on the list of factors that cause premature mortality in developing nations. The chronic nature of hypertension necessitates a comprehensive health system response that combines a skilled workforce, accessible technologies, and empowering individuals to take care of themselves. In India, there are an estimated 29.8 million individuals with hypertension, 16.1 million of whom live in cities and 13.7 million in rural areas. In Tamil Nadu, urban hypertension incidence was 32.6%, while rural hypertension prevalence was 23.4%. This indicates that 1.2 crore individuals in the state have high blood pressure. According to the Chennai Urban Rural Epidemiology Study (CURES), 17.1% of women and 23.2% of males in Chennai have hypertension. Aim: The purpose of this research was to evaluate the effects of a comprehensive nursing care package on patients' hypertension in a particular hospital in Chennai. Methods: A Quasi-Experimental pre-test, and post-test with a control group interrupted time series design was undertaken for the study. The samples for the study were the hypertensive clients who visited outpatient departments in Pavithra Hospital and Saravana hospital, Chennai, and the sample size for the study was 15 each for the experimental and control group Results: The comprehensive nursing care package is the lifestyle modification of hypertension which was given using Nurse-Led program, Counselling and Warm foot Bath therapy. SBP score is statistically significant different between pre-test and posttest-III ( F = 20.55, P ≤ 0.001).