E-ISSN 2063-5346
 

Research Article 


PREPARATION AND CHARACTERIZATION OF LIPIDPOLYMER-HYBRID NANO PARTICLES OF ANTIALZHEIMER’S DRUGS- A RESEARCH

YELLAREDDY CHALLA, V. SENTHIL, N. JAWAHAR.

Abstract
Tramiprosate and luteolin are used as a means of treating Alzheimer's disease. Tramiprosate is a GABA-A
receptor functional agonist due to this structure being similar to the GABA structure. Due to its tremendous antioxidant
action, luteolin may be able to reduce the neurotoxicity of Aβ fragment 25-35 (Aβ 25-35) in the cortical neurons of mice. It
has been widely established that neuroinflammation and glutamatergic excitotoxicity, which are linked to neuronal
dysfunction and that they both contribute significantly to the onset and development of both locomotor and neurocognitive
diseases. The goals of this work were to characterise and examine the physicochemical features of each solid form of an
active pharmaceutical ingredient (API), each of which can display distinct physicochemical characteristics.

Key words: Alzheimer’s disease, Gama Amino Butyric Acid, Amyloid beta, Lipid-Polymer Hybrid Nanoparticles.


 
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Pubmed Style

YELLAREDDY CHALLA, V. SENTHIL, N. JAWAHAR. PREPARATION AND CHARACTERIZATION OF LIPIDPOLYMER-HYBRID NANO PARTICLES OF ANTIALZHEIMER’S DRUGS- A RESEARCH. ECB. 2022; 11(4): 31-40. doi:10.31838/ecb/2022.11.04.005


Web Style

YELLAREDDY CHALLA, V. SENTHIL, N. JAWAHAR. PREPARATION AND CHARACTERIZATION OF LIPIDPOLYMER-HYBRID NANO PARTICLES OF ANTIALZHEIMER’S DRUGS- A RESEARCH. https://www.eurchembull.com/?mno=96463 [Access: September 25, 2022]. doi:10.31838/ecb/2022.11.04.005


AMA (American Medical Association) Style

YELLAREDDY CHALLA, V. SENTHIL, N. JAWAHAR. PREPARATION AND CHARACTERIZATION OF LIPIDPOLYMER-HYBRID NANO PARTICLES OF ANTIALZHEIMER’S DRUGS- A RESEARCH. ECB. 2022; 11(4): 31-40. doi:10.31838/ecb/2022.11.04.005



Vancouver/ICMJE Style

YELLAREDDY CHALLA, V. SENTHIL, N. JAWAHAR. PREPARATION AND CHARACTERIZATION OF LIPIDPOLYMER-HYBRID NANO PARTICLES OF ANTIALZHEIMER’S DRUGS- A RESEARCH. ECB. (2022), [cited September 25, 2022]; 11(4): 31-40. doi:10.31838/ecb/2022.11.04.005



Harvard Style

YELLAREDDY CHALLA, V. SENTHIL, N. JAWAHAR (2022) PREPARATION AND CHARACTERIZATION OF LIPIDPOLYMER-HYBRID NANO PARTICLES OF ANTIALZHEIMER’S DRUGS- A RESEARCH. ECB, 11 (4), 31-40. doi:10.31838/ecb/2022.11.04.005



Turabian Style

YELLAREDDY CHALLA, V. SENTHIL, N. JAWAHAR. 2022. PREPARATION AND CHARACTERIZATION OF LIPIDPOLYMER-HYBRID NANO PARTICLES OF ANTIALZHEIMER’S DRUGS- A RESEARCH. European Chemical Bulletin, 11 (4), 31-40. doi:10.31838/ecb/2022.11.04.005



Chicago Style

YELLAREDDY CHALLA, V. SENTHIL, N. JAWAHAR. "PREPARATION AND CHARACTERIZATION OF LIPIDPOLYMER-HYBRID NANO PARTICLES OF ANTIALZHEIMER’S DRUGS- A RESEARCH." European Chemical Bulletin 11 (2022), 31-40. doi:10.31838/ecb/2022.11.04.005



MLA (The Modern Language Association) Style

YELLAREDDY CHALLA, V. SENTHIL, N. JAWAHAR. "PREPARATION AND CHARACTERIZATION OF LIPIDPOLYMER-HYBRID NANO PARTICLES OF ANTIALZHEIMER’S DRUGS- A RESEARCH." European Chemical Bulletin 11.4 (2022), 31-40. Print. doi:10.31838/ecb/2022.11.04.005



APA (American Psychological Association) Style

YELLAREDDY CHALLA, V. SENTHIL, N. JAWAHAR (2022) PREPARATION AND CHARACTERIZATION OF LIPIDPOLYMER-HYBRID NANO PARTICLES OF ANTIALZHEIMER’S DRUGS- A RESEARCH. European Chemical Bulletin, 11 (4), 31-40. doi:10.31838/ecb/2022.11.04.005