SYNTHESIS AND CHARACTERIZATION OF TRIFLUOROMETHYL SUBSTITUTED PYRAZOLE DERIVATIVES

Authors

  • Jignesh K Sutariya, Jayesh L Gajera, Jigar Soni, Haresh Ram, Pankaj K. Godhaviya Silaev

Abstract

A series of functionally substituted pyrazole compounds have been synthesized using classical chemistry. Here we synthesized
trifluoromethyl containing pyrazole compound by condensation of arylhydrazine derivative with ethyl (2E)-2-(ethoxymethylidene)-4,4,4-
trifluoro-3-oxobutanoate. Pyrazole moieties have essential pharmaceutical and agrochemical activities. Our research-based on
trifluoromethyl-containing pyrazole compounds synthesis also helps to improve biological activities due to fluorine binding affinity
properties.

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Published

2021-05-29