E-ISSN 2063-5346
 

Original Article 


EVALUATION OF SUB-ACUTE TOXICITY OF THE ETHANOLIC ROOT EXTRACT OF COLEUS VETTIVEROIDES IN ALBINO WISTAR RATS.

Kadmad Abdul Hameed Mohamed Azar, Devaraj Ezhilarasan, Dr. Suresh Rao, Kamatham Praveen.

Abstract
Background: In this study, we evaluated the oral sub-acute toxicity study of ethanolic roots extract of Coleus
vettiveroides on animal models. Methods:The sub-acute oral toxicity study was carried out as per OECD 423 guidelines. The
study was approved by the Institutional Animal Ethics Committee (IAEC). In sub-acute toxicity study, the oral dose (250, 500
and 1000 mg/kg) of coleus vettiveroides root extract was administered for 28 days to the three animals groups and their body
weight, hematological, serum hepatic biochemical parameters were evaluated and compared to normal group by sacrificing all
group animals. Results: Coleus vettiveroidestreated groups revealed neither mortality nor any significant changes were observed.
The result indicates that the oral administration of ethanolic root extract of Coleus vettiveroides plant did not produce any
significant toxic effect in albino wistar rats. Conclusions: The extract can be utilized safely for therapeutic use in pharmaceutical
formulations.

Key words: Sub acute toxicity, Coleus vettiveroides, hematology, liver.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Kadmad Abdul Hameed Mohamed Azar
Articles by Devaraj Ezhilarasan
Articles by Dr. Suresh Rao
Articles by Kamatham Praveen
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Kadmad Abdul Hameed Mohamed Azar, Devaraj Ezhilarasan, Dr. Suresh Rao, Kamatham Praveen. EVALUATION OF SUB-ACUTE TOXICITY OF THE ETHANOLIC ROOT EXTRACT OF COLEUS VETTIVEROIDES IN ALBINO WISTAR RATS.. ECB. 2022; 11(10): 95-101. doi:10.31838/ecb/2022.11.10.012


Web Style

Kadmad Abdul Hameed Mohamed Azar, Devaraj Ezhilarasan, Dr. Suresh Rao, Kamatham Praveen. EVALUATION OF SUB-ACUTE TOXICITY OF THE ETHANOLIC ROOT EXTRACT OF COLEUS VETTIVEROIDES IN ALBINO WISTAR RATS.. https://www.eurchembull.com/?mno=130979 [Access: November 29, 2022]. doi:10.31838/ecb/2022.11.10.012


AMA (American Medical Association) Style

Kadmad Abdul Hameed Mohamed Azar, Devaraj Ezhilarasan, Dr. Suresh Rao, Kamatham Praveen. EVALUATION OF SUB-ACUTE TOXICITY OF THE ETHANOLIC ROOT EXTRACT OF COLEUS VETTIVEROIDES IN ALBINO WISTAR RATS.. ECB. 2022; 11(10): 95-101. doi:10.31838/ecb/2022.11.10.012



Vancouver/ICMJE Style

Kadmad Abdul Hameed Mohamed Azar, Devaraj Ezhilarasan, Dr. Suresh Rao, Kamatham Praveen. EVALUATION OF SUB-ACUTE TOXICITY OF THE ETHANOLIC ROOT EXTRACT OF COLEUS VETTIVEROIDES IN ALBINO WISTAR RATS.. ECB. (2022), [cited November 29, 2022]; 11(10): 95-101. doi:10.31838/ecb/2022.11.10.012



Harvard Style

Kadmad Abdul Hameed Mohamed Azar, Devaraj Ezhilarasan, Dr. Suresh Rao, Kamatham Praveen (2022) EVALUATION OF SUB-ACUTE TOXICITY OF THE ETHANOLIC ROOT EXTRACT OF COLEUS VETTIVEROIDES IN ALBINO WISTAR RATS.. ECB, 11 (10), 95-101. doi:10.31838/ecb/2022.11.10.012



Turabian Style

Kadmad Abdul Hameed Mohamed Azar, Devaraj Ezhilarasan, Dr. Suresh Rao, Kamatham Praveen. 2022. EVALUATION OF SUB-ACUTE TOXICITY OF THE ETHANOLIC ROOT EXTRACT OF COLEUS VETTIVEROIDES IN ALBINO WISTAR RATS.. European Chemical Bulletin, 11 (10), 95-101. doi:10.31838/ecb/2022.11.10.012



Chicago Style

Kadmad Abdul Hameed Mohamed Azar, Devaraj Ezhilarasan, Dr. Suresh Rao, Kamatham Praveen. "EVALUATION OF SUB-ACUTE TOXICITY OF THE ETHANOLIC ROOT EXTRACT OF COLEUS VETTIVEROIDES IN ALBINO WISTAR RATS.." European Chemical Bulletin 11 (2022), 95-101. doi:10.31838/ecb/2022.11.10.012



MLA (The Modern Language Association) Style

Kadmad Abdul Hameed Mohamed Azar, Devaraj Ezhilarasan, Dr. Suresh Rao, Kamatham Praveen. "EVALUATION OF SUB-ACUTE TOXICITY OF THE ETHANOLIC ROOT EXTRACT OF COLEUS VETTIVEROIDES IN ALBINO WISTAR RATS.." European Chemical Bulletin 11.10 (2022), 95-101. Print. doi:10.31838/ecb/2022.11.10.012



APA (American Psychological Association) Style

Kadmad Abdul Hameed Mohamed Azar, Devaraj Ezhilarasan, Dr. Suresh Rao, Kamatham Praveen (2022) EVALUATION OF SUB-ACUTE TOXICITY OF THE ETHANOLIC ROOT EXTRACT OF COLEUS VETTIVEROIDES IN ALBINO WISTAR RATS.. European Chemical Bulletin, 11 (10), 95-101. doi:10.31838/ecb/2022.11.10.012