E-ISSN 2063-5346
 

Original Article 


Efficacy of Onchidiid Slug (Onchidiium typhae) Ethanolic Extract Against Bacterial and Fungal Grown in Biofilm Cultures

Bambang Wijianto, Hasyrul Hamzah.

Abstract
Staphylococcus aureus, Escherichia coli, and Candida albicans are opportunistic species responsible for clinical infection by producing biofilms. In the form of biofilm, they are more resistant to various antimicrobial agents. This study at to determine the biofilm activity of onchidiid slug extract against S.aureus, E.coli, and C.albicans. The microtiter broth method was used to measure the inhibitory and eradicating ability of S.aureus, E.coli, and C.albicans biofilms. In samples of onchidiid slug ethanol extract at a level of 1%, the S. aureus biofilm was inhibited by 63.89%. The MBIC value is at a level of 0.5%. The inhibitory activity on E.coli biofilm was 85% at 1%, with the MBIC value at 0.5%. Onchidiid slug ethanol extract samples also showed inhibitory activity on the C.albicans biofilm of 67.95% at a level of 1% with an MBIC value of 0.25%. The test results showed that extract could be developed as a new antibiofilm candidate for treating S.aureus, E.coli, and C.albicans biofilm infections.

Key words: Onchidium typhae, antibiofilm, Onchidiid slug extract ethanolic


 
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How to Cite this Article
Pubmed Style

Wijianto B, Hamzah H. Efficacy of Onchidiid Slug (Onchidiium typhae) Ethanolic Extract Against Bacterial and Fungal Grown in Biofilm Cultures. ECB. 2022; 11(10): 112-116. doi:10.31838/ecb/2022.11.10.015


Web Style

Wijianto B, Hamzah H. Efficacy of Onchidiid Slug (Onchidiium typhae) Ethanolic Extract Against Bacterial and Fungal Grown in Biofilm Cultures. https://www.eurchembull.com/?mno=122201 [Access: November 29, 2022]. doi:10.31838/ecb/2022.11.10.015


AMA (American Medical Association) Style

Wijianto B, Hamzah H. Efficacy of Onchidiid Slug (Onchidiium typhae) Ethanolic Extract Against Bacterial and Fungal Grown in Biofilm Cultures. ECB. 2022; 11(10): 112-116. doi:10.31838/ecb/2022.11.10.015



Vancouver/ICMJE Style

Wijianto B, Hamzah H. Efficacy of Onchidiid Slug (Onchidiium typhae) Ethanolic Extract Against Bacterial and Fungal Grown in Biofilm Cultures. ECB. (2022), [cited November 29, 2022]; 11(10): 112-116. doi:10.31838/ecb/2022.11.10.015



Harvard Style

Wijianto, B. & Hamzah, . H. (2022) Efficacy of Onchidiid Slug (Onchidiium typhae) Ethanolic Extract Against Bacterial and Fungal Grown in Biofilm Cultures. ECB, 11 (10), 112-116. doi:10.31838/ecb/2022.11.10.015



Turabian Style

Wijianto, Bambang, and Hasyrul Hamzah. 2022. Efficacy of Onchidiid Slug (Onchidiium typhae) Ethanolic Extract Against Bacterial and Fungal Grown in Biofilm Cultures. European Chemical Bulletin, 11 (10), 112-116. doi:10.31838/ecb/2022.11.10.015



Chicago Style

Wijianto, Bambang, and Hasyrul Hamzah. "Efficacy of Onchidiid Slug (Onchidiium typhae) Ethanolic Extract Against Bacterial and Fungal Grown in Biofilm Cultures." European Chemical Bulletin 11 (2022), 112-116. doi:10.31838/ecb/2022.11.10.015



MLA (The Modern Language Association) Style

Wijianto, Bambang, and Hasyrul Hamzah. "Efficacy of Onchidiid Slug (Onchidiium typhae) Ethanolic Extract Against Bacterial and Fungal Grown in Biofilm Cultures." European Chemical Bulletin 11.10 (2022), 112-116. Print. doi:10.31838/ecb/2022.11.10.015



APA (American Psychological Association) Style

Wijianto, B. & Hamzah, . H. (2022) Efficacy of Onchidiid Slug (Onchidiium typhae) Ethanolic Extract Against Bacterial and Fungal Grown in Biofilm Cultures. European Chemical Bulletin, 11 (10), 112-116. doi:10.31838/ecb/2022.11.10.015