EXPERIMENTAL AND PREDICTED SOLUBILITIES OF 3,4-DIMETHOXYBENZOIC ACID IN SELECT ORGANIC SOLVENTS OF VARYING POLARITY AND HYDROGEN-BONDING CHARACTER

Kaci R. Bowen, Timothy W. Stephens, Helen Lu, Kalpana Satish, Danyang Shan, William E. Acree, Michael H. Abraham

Abstract


Experimental solubilities are reported for 3,4-dimethoxybenzoic acid dissolved in 16 alcohol, 5 alkyl alkanoate, 5 alkoxyalcohol and 6 ether solvents.  The measured solubility data were correlated with the Abraham solvation parameter model.  Mathematical expressions based on the Abraham model predicted the observed molar solubilities to within 0.083 log units.

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DOI: http://dx.doi.org/10.17628/ecb.2013.2.577-583

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