A CONVENIENT WAY for the preparation of novel thiourea derivatives containing biologically active quinazoline moiety

Sohail Saeed, Rizwan Hussain


A series of new thiourea derivatives containing quinazoline-4(3H)-one framework (3a-d) was successfully synthesized and characterized by IR, 1H-NMR, 13C-NMR spectroscopy, ESI Mass spectrometry and elemental analysis. Variation in the functional group at the phenyl ring led to set of compounds bearing quinazoline-4(3H)-one accommodated substituted phenyl thioureas.

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DOI: http://dx.doi.org/10.17628/ecb.2013.2.465-467


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