ONE-POT SYNTHESIS OF PYRANO[2,3-c]PYRAZOLES USING LEMON PEEL POWDER AS A GREEN AND NATURAL CATALYST

S. S. Ghodke, S.U. Tekale, R.D. Pathrikar, P.M. Khandare, Laszlo Kotai, R.P. Pawar

Abstract


A simple one-pot four-component synthesis of pyrano[2,3-c]pyrazoles has been achieved by the condensation of aldehydes, malononitrile, ethyl acetoacetate and hydrazine hydrate using lemon peel powder as a natural catalyst in ethanol under reflux condition. The advantages of this reaction are less reaction time, high yield, easy availability of the catalyst and green nature of the protocol.

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DOI: http://dx.doi.org/10.17628/ecb.2020.9.38-42

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