ONE-POT SYNTHESIS OF PHTHALAZIN-4-HETEROYL-4H-PYRAN DERIVATIVES IN [BMIM][OH]

Loka Maheshwari, B. Satyanarayana

Abstract


A [bmim][OH] mediated, green and efficient synthesis of phthalazines derivatives have been developed by condensing phthalic acid (1), ethyl cyanohydrazide (2), heteroaromatic aldehydes (3a-3f) and active methylene compounds (4) at 60-65 oC for 60-90 min. The importance of this method includes shorter reaction time and high yield.

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DOI: http://dx.doi.org/10.17628/ecb.2019.8.363-367

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