SYNTHESIS OF 1H-INDAZOLES USING LEMON PEEL POWDER AS A NATURAL, GREEN AND EFFICIENT CATALYST UNDER ULTRASOUND IRRADIATION

Swati S. Ghodke, Priya M. Khandare, Sadhana N. Salve, Pravin S. Kendrekar, Dhanaji Rajani, R. P. Pawar

Abstract


Bioactive 1H-indazoles were synthesized from 2-substituted aromatic aldehyde and hydrazine hydrate using DMSO and Lemon peel powder as a green and efficient natural catalyst. Good yield of products were obtained in DMSO solvent using a catalytic amount of Lemon peel powder. In comparison to other reported conventional methods, this method affords good yield under ultrasonic irradiation.

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DOI: http://dx.doi.org/10.17628/ecb.2019.8.405-408

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