ONE POT SYNTHESIS OF PYRANOPYRAZOLE USING SODIUM LACTATE AS AN EFFICIENT CATALYST

Jayant P. Sonar, S. D. Pardeshi, S. A. Dokhe, G. M. Bhavar, S. U. Tekale, A. M. Zine, S. N. Thore

Abstract


An efficient one pot synthesis of pyranopyrazoles has been achieved by the four-component condensation of hydrazine hydrate, ethyl acetoacetate, aldehydes and malononitrile using sodium lactate as a catalyst in aqueous ethanolic medium under reflux condition. The method is simple and green to afford pyranopyrazoles in a short time. It provides a new base catalyst that readily gives product from moderate to excellent yields

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DOI: http://dx.doi.org/10.17628/ecb.2019.8.207-211

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