Au-MOPS(3-MORPHOLINOPROPANE-1-SULFONIC ACID) COUPLED CATALYST FOR THE SYNTHESIS OF 3-AMINOALKYLATED INDOLES

S. B. Sapkal, S. Y. Guhe, S.N. Harke, B.R. Madje, S.S. Gadekar

Abstract


Gold nanoparticles (Au NPs) coupled with 3-morpholinopropane-1-sulfonic acid (MOPS) for catalytic performance to the cyclocondensation reaction of aromatic/heteroaromatic/aliphatic aldehydes, indole and aromatic/heteroaromatic amines have been demonstrated for the first time in favour of 3-aminoalkylated indoles in ethyl alcohol at reflux temperature. Reaction conditions are just like ambient nevertheless all chemical transformations completed smoothly contributing worthwhile for the synthesis of 3-aminoalkylated indoles.

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DOI: http://dx.doi.org/10.17628/ecb.2020.9.82-86

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