CONVENIENT SYNTHESIS OF NEW 7-METHYLTETRAZOLO[1,5-a]QUINOLINE-4-CARBALDEHYDE DERIVATIVES

Ibrahim Ali M. Radini

Abstract


7-Methyltetrazolo[1,5-a]quinoline-4-carbaldehyde (1) was reacted with thiosemicarbazide to give the appropriate thiosemicarbazone (2). Compound (2) was reacted with different α-halocarbonyl compounds such as phenacyl bromide, hydrazonoyl chlorides and α-chloroacetic acid to afford thiazoles (4), aryldiazenylthiazoles (6), and thiazolidin-4-one (8), respectively. A series of 7-methyltetrazolo[1,5-a]quinoline derivatives, such as 2-imino-2H-chromene (11), arylacrylohydrazides (13), (15) and (17) and (heteroarylethylidene) acrylohydrazides (19), (21) and (23) has been synthesized. The structures of the newly synthesized compounds have been confirmed by spectral and elemental analyses.

Full Text:

PDF


DOI: http://dx.doi.org/10.17628/ecb.2016.5.232-237

Refbacks

  • There are currently no refbacks.


 

*********************** European Chemical Bulletin *******************