DETERMINATION OF CAFFEINE CONTENT FROM DIFFERENT PHARMACEUTICAL AND NATURAL PRODUCTS

Andrea Corciova, Bianca Ivanescu

Abstract


The present study focuses on the quantification of caffeine from 11 pharmaceutical and natural products. Pharmaceutical products were purchased from pharmacy and include 4 types of tablets and 1 suppository type product. Natural products were purchased from specialty stores and comprise green tea, black tea and different kinds of coffee. Some of the quality parameters like friability and disintegration time for tablets, melting behavior, deformation temperature and time of deformation for suppositories were determined.  The caffeine content was determined using UV spectrophotometric methods by measuring the absorbance at 272 nm, after separating the caffeine from the others active ingredients and excipients. The results showed that caffeine content in pharmaceutical products purchased from pharmacies is in the range recommended by European and Romanian Pharmacopoeia. In the case of natural products, the caffeine content decreases in the following order: bulk coffee beans freshly ground > ground coffee packed > black tea > green tea > decaffeinated coffee.

Full Text:

pdf


DOI: http://dx.doi.org/10.17628/ecb.2016.5.138-141

Refbacks

  • There are currently no refbacks.


 

*********************** European Chemical Bulletin *******************