THE LONG TERM EFFECT OF MATERNAL OLIVE OIL SUPPLEMENTATION ON METABOLIC AND REDOX STATUS IN OFFSPRING OF OBESE RATS

Salima Derouiche, Fatima Zohra Baba Ahmed, Hafida Merzouk, Samira Bouanane, Abdettouweb Saidi, Sid Ahmed Merzouk, Narce Michel

Abstract


The aim of this study was designed to determine whether maternal supplementation with olive oil influence plasma lipid profile and oxidant/antioxidant status later in life of rats with cafeteria- diet-fed during gestation and in their offspring throughout adulthood. Altering the fatty acid profile of rat diets during the gestation has long-term consequences for the growth and development of their offspring. Our results clearly demonstrate that maternal intake of olive oil before gestation, during gestation and during lactation display remarkable health benefits for the prevention of obesity and associated metabolic disorders by decreasing the lipoprotein metabolism and oxidant/antioxidant status alterations brought about by obesity in offspring at birth until adulthood.

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DOI: http://dx.doi.org/10.17628/ecb.2016.5.8-13

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