Convenient Synthesis of some new purine analogues incorporating furan nucleus

Sayed Said Mostafa, Ahmad Maher Mohamed Salem Nada

Abstract


Sodium 3-(furan-2-yl)-3-oxoprop-1-en-1-olate was used as precursor for synthesis of some novel derivatives of various fused heterocyclic ring systems namely pyrazolo[1,5-a]pyrimidines, triazolo[1,5-a]pyrimidines, benzo[4,5]imidazo-[l,2-a]pyrimidines, pyrazolo[5,l-c]triazines, [l,2,4]triazolo[4,3-c]triazines, benzo[4,5]imidazo[2,1-c]triazines. The structures of the newly synthesized were established on the basis of their spectral data, elemental analyses and alternate synthetic route whenever possible.

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DOI: http://dx.doi.org/10.17628/ecb.2015.4.50-59

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