AN EFFICIENT SYNTHESIS OF SOME NOVEL 5,7-DIARYLPYRIDO[4,3-D]PYRIMIDINES

V. Vijayakumar, P. Karthikeyan Karthikeyan, S. Sarveswari

Abstract


The 4-oxo-N, 2, 6-triphenyl piperidine-3-carboxamides (3a-f) were synthesized using arlyaldehydes, ammonium acetate and acetoacetanilide, which in turn converted into  5,6,7,8-tetrahydro-4-hydroxy-5,7-diarylpyrido[4,3-d]pyrimidin-2(3H)-ones (4a-f), 2-amino-5,6,7,8-tetrahydro-5,7-diarylpyrido[4,3-d]pyrimidin-4-ols (5a-f) by condensing with guanidine carbonate, and urea.

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DOI: http://dx.doi.org/10.17628/ecb.2014.3.624-626

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