E-ISSN 2063-5346
 

Research Article 


SYNTHESIS AND BIOLOGICAL ACTIVITY OF NEW COMPOUNDS OF FIVE AND SIX MEMBERED RINGS INCORPORATING TO COUMARIN DERIVATIVES

Mohaned Mohammed Sahb, Zeina Mohammed Kadam.

Abstract
Reaction and condensation between 2-chloroquinoline-3-carbaldehyde and substituted coumarone to Produced
chalcone, the derivative (3) was adopted as chalcone to react with different compound such as ethyl cyanoacetate, ammonia, urea,
thiourea, phenylthiosemicarbazide, and hydroxyl amine hydrochloride to produced new ring of pyranone, pyridine, pyrimidine,
pyrazole and isoxazole compounds (4,5,6,7,8,9) respectively, were identified their structure by infrared spectroscopy, Nuclear
magnetic and elemental analysis. Pharmaceutical applications have been studied for the prepared compound and achievement with
different drugs.

Key words: Polycyclic chloroquinolines, pyrimidines, coumarin, pyranone, isoxazoles


 
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Pubmed Style

Mohaned Mohammed Sahb, Zeina Mohammed Kadam. SYNTHESIS AND BIOLOGICAL ACTIVITY OF NEW COMPOUNDS OF FIVE AND SIX MEMBERED RINGS INCORPORATING TO COUMARIN DERIVATIVES . ECB. 2022; 11(4): 87-92. doi:10.31838/ecb/2022.11.04.013


Web Style

Mohaned Mohammed Sahb, Zeina Mohammed Kadam. SYNTHESIS AND BIOLOGICAL ACTIVITY OF NEW COMPOUNDS OF FIVE AND SIX MEMBERED RINGS INCORPORATING TO COUMARIN DERIVATIVES . https://www.eurchembull.com/?mno=96589 [Access: August 09, 2022]. doi:10.31838/ecb/2022.11.04.013


AMA (American Medical Association) Style

Mohaned Mohammed Sahb, Zeina Mohammed Kadam. SYNTHESIS AND BIOLOGICAL ACTIVITY OF NEW COMPOUNDS OF FIVE AND SIX MEMBERED RINGS INCORPORATING TO COUMARIN DERIVATIVES . ECB. 2022; 11(4): 87-92. doi:10.31838/ecb/2022.11.04.013



Vancouver/ICMJE Style

Mohaned Mohammed Sahb, Zeina Mohammed Kadam. SYNTHESIS AND BIOLOGICAL ACTIVITY OF NEW COMPOUNDS OF FIVE AND SIX MEMBERED RINGS INCORPORATING TO COUMARIN DERIVATIVES . ECB. (2022), [cited August 09, 2022]; 11(4): 87-92. doi:10.31838/ecb/2022.11.04.013



Harvard Style

Mohaned Mohammed Sahb, Zeina Mohammed Kadam (2022) SYNTHESIS AND BIOLOGICAL ACTIVITY OF NEW COMPOUNDS OF FIVE AND SIX MEMBERED RINGS INCORPORATING TO COUMARIN DERIVATIVES . ECB, 11 (4), 87-92. doi:10.31838/ecb/2022.11.04.013



Turabian Style

Mohaned Mohammed Sahb, Zeina Mohammed Kadam. 2022. SYNTHESIS AND BIOLOGICAL ACTIVITY OF NEW COMPOUNDS OF FIVE AND SIX MEMBERED RINGS INCORPORATING TO COUMARIN DERIVATIVES . European Chemical Bulletin, 11 (4), 87-92. doi:10.31838/ecb/2022.11.04.013



Chicago Style

Mohaned Mohammed Sahb, Zeina Mohammed Kadam. "SYNTHESIS AND BIOLOGICAL ACTIVITY OF NEW COMPOUNDS OF FIVE AND SIX MEMBERED RINGS INCORPORATING TO COUMARIN DERIVATIVES ." European Chemical Bulletin 11 (2022), 87-92. doi:10.31838/ecb/2022.11.04.013



MLA (The Modern Language Association) Style

Mohaned Mohammed Sahb, Zeina Mohammed Kadam. "SYNTHESIS AND BIOLOGICAL ACTIVITY OF NEW COMPOUNDS OF FIVE AND SIX MEMBERED RINGS INCORPORATING TO COUMARIN DERIVATIVES ." European Chemical Bulletin 11.4 (2022), 87-92. Print. doi:10.31838/ecb/2022.11.04.013



APA (American Psychological Association) Style

Mohaned Mohammed Sahb, Zeina Mohammed Kadam (2022) SYNTHESIS AND BIOLOGICAL ACTIVITY OF NEW COMPOUNDS OF FIVE AND SIX MEMBERED RINGS INCORPORATING TO COUMARIN DERIVATIVES . European Chemical Bulletin, 11 (4), 87-92. doi:10.31838/ecb/2022.11.04.013